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P21 – 10mg

(1 customer review)

P21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclinCDK2, –CDK1, and –CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase. The binding of p21 to CDK complexes occurs through p21’s N-terminal domain, which is homologous to the other CIP/KIP CDK inhibitors p27 and p57. Specifically it contains a Cy1 motif in the N-terminal half, and weaker Cy2 motif in the C-terminal domain that allow it to bind CDK in a region that blocks its ability to complex with cyclins and thus prevent CDK activation. For more research information, please visit the following Wikipedia article.

Important Information About This Research Product:

  1. Your vials are not empty. The product is at the bottom of the vial.
  2. All peptides come in a lyophilized (freeze-dried) powder, that must be reconstituted with bacteriostatic water (this is not something that we carry).
  3. Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store ≤ 4°C.
  4. All products purchased are for laboratory & research use ONLY, this means we cannot provide any further instructions on reconstitution and/or dosing.

$99.99

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80 in stock (can be backordered)

Quantity Discounted Price
2 - 9 $96.99
10 - 19 $93.99
20 + $89.99
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Lyophilization is defined as a freeze-drying process that removes water from a product after it is frozen and placed under a vacuum.

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Additional information

Weight .284 oz

Description

P21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclinCDK2, –CDK1, and –CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase. The binding of p21 to CDK complexes occurs through p21’s N-terminal domain, which is homologous to the other CIP/KIP CDK inhibitors p27 and p57. Specifically it contains a Cy1 motif in the N-terminal half, and weaker Cy2 motif in the C-terminal domain that allow it to bind CDK in a region that blocks its ability to complex with cyclins and thus prevent CDK activation. For more research information, please visit the following Wikipedia article.

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Synonyms

CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1, cyclin-dependent kinase inhibitor 1A, cyclin dependent kinase inhibitor 1A

Appearance

Lyophilized Powder

CAS

1394011-91-6

Sequence

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((1r,4r)-4-(5-(trifluoromethyl)pyridin-2-yloxy)cyclohexyl)urea

Structure

Molecular Formula

C20H18ClF6N3O2

Molecular Weight

481.82 g/mol

Storage

Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store @ 4°C.

1 review for P21 – 10mg

  1. Hugo Cohen

    Great products and quick shipping. Highly recommend if your practice is in the market for the products they sell.

Add a review

Your email address will not be published. Required fields are marked *

Additional information

Weight .284 oz

Description

P21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclinCDK2, –CDK1, and –CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase. The binding of p21 to CDK complexes occurs through p21’s N-terminal domain, which is homologous to the other CIP/KIP CDK inhibitors p27 and p57. Specifically it contains a Cy1 motif in the N-terminal half, and weaker Cy2 motif in the C-terminal domain that allow it to bind CDK in a region that blocks its ability to complex with cyclins and thus prevent CDK activation. For more research information, please visit the following Wikipedia article.

Synonyms

CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1, cyclin-dependent kinase inhibitor 1A, cyclin dependent kinase inhibitor 1A

Appearance

Lyophilized Powder

CAS

1394011-91-6

Sequence

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((1r,4r)-4-(5-(trifluoromethyl)pyridin-2-yloxy)cyclohexyl)urea

Structure

Molecular Formula

C20H18ClF6N3O2

Molecular Weight

481.82 g/mol

Storage

Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store @ 4°C.

1 review for P21 – 10mg

  1. Hugo Cohen

    Great products and quick shipping. Highly recommend if your practice is in the market for the products they sell.

Add a review

Your email address will not be published. Required fields are marked *

Additional information

Weight .284 oz

Description

P21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclinCDK2, –CDK1, and –CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase. The binding of p21 to CDK complexes occurs through p21’s N-terminal domain, which is homologous to the other CIP/KIP CDK inhibitors p27 and p57. Specifically it contains a Cy1 motif in the N-terminal half, and weaker Cy2 motif in the C-terminal domain that allow it to bind CDK in a region that blocks its ability to complex with cyclins and thus prevent CDK activation. For more research information, please visit the following Wikipedia article.

Synonyms

CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1, cyclin-dependent kinase inhibitor 1A, cyclin dependent kinase inhibitor 1A

Appearance

Lyophilized Powder

CAS

1394011-91-6

Sequence

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((1r,4r)-4-(5-(trifluoromethyl)pyridin-2-yloxy)cyclohexyl)urea

Structure

Molecular Formula

C20H18ClF6N3O2

Molecular Weight

481.82 g/mol

Storage

Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store @ 4°C.

1 review for P21 – 10mg

  1. Hugo Cohen

    Great products and quick shipping. Highly recommend if your practice is in the market for the products they sell.

Add a review

Your email address will not be published. Required fields are marked *

Additional information

Weight .284 oz

Description

P21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclinCDK2, –CDK1, and –CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase. The binding of p21 to CDK complexes occurs through p21’s N-terminal domain, which is homologous to the other CIP/KIP CDK inhibitors p27 and p57. Specifically it contains a Cy1 motif in the N-terminal half, and weaker Cy2 motif in the C-terminal domain that allow it to bind CDK in a region that blocks its ability to complex with cyclins and thus prevent CDK activation. For more research information, please visit the following Wikipedia article.

Synonyms

CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1, cyclin-dependent kinase inhibitor 1A, cyclin dependent kinase inhibitor 1A

Appearance

Lyophilized Powder

CAS

1394011-91-6

Sequence

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((1r,4r)-4-(5-(trifluoromethyl)pyridin-2-yloxy)cyclohexyl)urea

Structure

Molecular Formula

C20H18ClF6N3O2

Molecular Weight

481.82 g/mol

Storage

Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store @ 4°C.

1 review for P21 – 10mg

  1. Hugo Cohen

    Great products and quick shipping. Highly recommend if your practice is in the market for the products they sell.

Add a review

Your email address will not be published. Required fields are marked *

Additional information

Weight .284 oz

Description

P21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclinCDK2, –CDK1, and –CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase. The binding of p21 to CDK complexes occurs through p21’s N-terminal domain, which is homologous to the other CIP/KIP CDK inhibitors p27 and p57. Specifically it contains a Cy1 motif in the N-terminal half, and weaker Cy2 motif in the C-terminal domain that allow it to bind CDK in a region that blocks its ability to complex with cyclins and thus prevent CDK activation. For more research information, please visit the following Wikipedia article.

Synonyms

CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1, cyclin-dependent kinase inhibitor 1A, cyclin dependent kinase inhibitor 1A

Appearance

Lyophilized Powder

CAS

1394011-91-6

Sequence

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((1r,4r)-4-(5-(trifluoromethyl)pyridin-2-yloxy)cyclohexyl)urea

Structure

Molecular Formula

C20H18ClF6N3O2

Molecular Weight

481.82 g/mol

Storage

Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store @ 4°C.

1 review for P21 – 10mg

  1. Hugo Cohen

    Great products and quick shipping. Highly recommend if your practice is in the market for the products they sell.

Add a review

Your email address will not be published. Required fields are marked *

Additional information

Weight .284 oz

Description

P21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclinCDK2, –CDK1, and –CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase. The binding of p21 to CDK complexes occurs through p21’s N-terminal domain, which is homologous to the other CIP/KIP CDK inhibitors p27 and p57. Specifically it contains a Cy1 motif in the N-terminal half, and weaker Cy2 motif in the C-terminal domain that allow it to bind CDK in a region that blocks its ability to complex with cyclins and thus prevent CDK activation. For more research information, please visit the following Wikipedia article.

Synonyms

CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1, cyclin-dependent kinase inhibitor 1A, cyclin dependent kinase inhibitor 1A

Appearance

Lyophilized Powder

CAS

1394011-91-6

Sequence

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((1r,4r)-4-(5-(trifluoromethyl)pyridin-2-yloxy)cyclohexyl)urea

Structure

Molecular Formula

C20H18ClF6N3O2

Molecular Weight

481.82 g/mol

Storage

Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store @ 4°C.

1 review for P21 – 10mg

  1. Hugo Cohen

    Great products and quick shipping. Highly recommend if your practice is in the market for the products they sell.

Add a review

Your email address will not be published. Required fields are marked *

Additional information

Weight .284 oz

Description

P21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclinCDK2, –CDK1, and –CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase. The binding of p21 to CDK complexes occurs through p21’s N-terminal domain, which is homologous to the other CIP/KIP CDK inhibitors p27 and p57. Specifically it contains a Cy1 motif in the N-terminal half, and weaker Cy2 motif in the C-terminal domain that allow it to bind CDK in a region that blocks its ability to complex with cyclins and thus prevent CDK activation. For more research information, please visit the following Wikipedia article.

Synonyms

CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1, cyclin-dependent kinase inhibitor 1A, cyclin dependent kinase inhibitor 1A

Appearance

Lyophilized Powder

CAS

1394011-91-6

Sequence

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((1r,4r)-4-(5-(trifluoromethyl)pyridin-2-yloxy)cyclohexyl)urea

Structure

Molecular Formula

C20H18ClF6N3O2

Molecular Weight

481.82 g/mol

Storage

Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store @ 4°C.

1 review for P21 – 10mg

  1. Hugo Cohen

    Great products and quick shipping. Highly recommend if your practice is in the market for the products they sell.

Add a review

Your email address will not be published. Required fields are marked *

Additional information

Weight .284 oz

Description

P21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclinCDK2, –CDK1, and –CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase. The binding of p21 to CDK complexes occurs through p21’s N-terminal domain, which is homologous to the other CIP/KIP CDK inhibitors p27 and p57. Specifically it contains a Cy1 motif in the N-terminal half, and weaker Cy2 motif in the C-terminal domain that allow it to bind CDK in a region that blocks its ability to complex with cyclins and thus prevent CDK activation. For more research information, please visit the following Wikipedia article.

Synonyms

CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1, cyclin-dependent kinase inhibitor 1A, cyclin dependent kinase inhibitor 1A

Appearance

Lyophilized Powder

CAS

1394011-91-6

Sequence

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((1r,4r)-4-(5-(trifluoromethyl)pyridin-2-yloxy)cyclohexyl)urea

Structure

Molecular Formula

C20H18ClF6N3O2

Molecular Weight

481.82 g/mol

Storage

Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store @ 4°C.

1 review for P21 – 10mg

  1. Hugo Cohen

    Great products and quick shipping. Highly recommend if your practice is in the market for the products they sell.

Add a review

Your email address will not be published. Required fields are marked *

Additional information

Weight .284 oz

Description

P21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclinCDK2, –CDK1, and –CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G1 and S phase. The binding of p21 to CDK complexes occurs through p21’s N-terminal domain, which is homologous to the other CIP/KIP CDK inhibitors p27 and p57. Specifically it contains a Cy1 motif in the N-terminal half, and weaker Cy2 motif in the C-terminal domain that allow it to bind CDK in a region that blocks its ability to complex with cyclins and thus prevent CDK activation. For more research information, please visit the following Wikipedia article.

Synonyms

CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1, cyclin-dependent kinase inhibitor 1A, cyclin dependent kinase inhibitor 1A

Appearance

Lyophilized Powder

CAS

1394011-91-6

Sequence

1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-((1r,4r)-4-(5-(trifluoromethyl)pyridin-2-yloxy)cyclohexyl)urea

Structure

Molecular Formula

C20H18ClF6N3O2

Molecular Weight

481.82 g/mol

Storage

Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store @ 4°C.

1 review for P21 – 10mg

  1. Hugo Cohen

    Great products and quick shipping. Highly recommend if your practice is in the market for the products they sell.

Add a review

Your email address will not be published. Required fields are marked *

1 review for P21 – 10mg

  1. Hugo Cohen

    Great products and quick shipping. Highly recommend if your practice is in the market for the products they sell.

Add a review

Your email address will not be published. Required fields are marked *