P21 – 10mg

P21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclin–CDK2, –CDK1, and –CDK4/6 complexes, and thus functions as a regulator of cell cycle progression at G₁ and S phase. The binding of p21 to CDK complexes occurs through p21’s N-terminal domain, which is homologous to the other CIP/KIP CDK inhibitors p27 and p57. Specifically it contains a Cy1 motif in the N-terminal half, and weaker Cy2 motif in the C-terminal domain that allow it to bind CDK in a region that blocks its ability to complex with cyclins and thus prevent CDK activation. For more research information, please visit the following Wikipedia article.

Important Information About This Research Product:

1. Your vials are not empty. The product is at the bottom of the vial.
2. All peptides come in a lyophilized (freeze-dried) powder, that must be reconstituted with bacteriostatic water (this is not something that we carry).
3. Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store ≤ 4°C.
4. All products purchased are for laboratory & research use ONLY, this means we cannot provide any further instructions on reconstitution and/or dosing.